Latest electrophoresis, proteins and free light chains

Here are my latest results.

Specific Proteins

Test Name    Result       AB    Normal Range   Units
IGG          466          L     600-1700       MG/DL
IGM          31           L     35-290         MG/DL
IGA          408          H     40-400         MG/DL

Electrophoresis

The SPE pattern demonstrates two bands of restricted mobility in the gamma region.

Immunofix, Serum

Monoclonal component typed as IgA Lambda. Concentration of monoclonal protein determined by serum protein electrophoresis is 0.4 g/dL.
Monoclonal component typed as IgA Lambda. Concentration of monoclonal protein determined by serum protein electrophoresis is 0.3 g/dL.
*Suggestive of a monoclonal component typed as IgG Kappa. Concentration of monoclonal protein is too low to accurately quantify.

* This is new! Previously, I’ve only ever had just two m-spikes. That’s not enough?  I vaguely remember seeing this on one other report, so maybe it’s something that comes and goes.  In any case, it’s not enough to measure, so I’m not alarmed.

Serum Free Light Chain Assay

Test Name                  Result     AB  Normal Range    Units
Kappa Free, Serum          0.1380     L   0.33-1.94       mg/dL
Lambda Free, Serum         1.24           0.57-2.63       mg/dL
K/L FLC Ratio              0.1113     L   0.26-1.65       mg/dL

Still, no myeloma treatment for over two years.

MRIs and Mutliple Myeloma and gadolinium, oh my!

Margaret’s blog has a few posts written about the use of gadolinium as a contrast agent.  I think it’s important for MM patients to know about this.  You can the read posts at her blog.  These are all the posts containing the word, “gadolinium.”
»The gadolinium used in MRIs makes myeloma cells proliferate

In other news, there’s not much going on.  Last week I got to participate in a local radio show with two of Moore County’s finest, Detective Sgt Donnie Shingleton and Sgt Tim Cameron, of the Moore County Sheriff’s Department.  The topic was home security, which included discussions about fraud.  My part was Internet fraud.  My words didn’t really come out right!

Ticket to Ride by Ed GormanI start a creative non-fiction class tomorrow, thanks to my sister, Rachel.  She’s encouraged me to git me some more learnin’ so’s I kin write better.

Monica and I are taping for another radio program this morning.  I’ll let you know how that one turns out.

How many of you bought Ed Gorman’s new book? If you haven’t gotten it yet, now’s a good time.  » Ticket to Ride by Ed Gorman.   He wrote something to me on the dedication page!

Required reading

I received the latest Sam McCain Mystery from Ed Gorman in today’s mail! It’s called “Ticket to Ride.” There was a Post-it® Flag on one of the pages, so I quickly opened the book to see what Ed wanted to draw my attention to. It was a lovely message for me on the dedication page! I’m deeply touched by this, so I think every one of you should buy a copy of the book.
For your convenience, I’m including an easy way to purchase the book right here. Please buy two: One for yourself and one as a gift for a family member or friend! It’s also available for Kindle and in large print.

 

Ticket to Ride

1965: America’s favorite small-town detective must solve the murder of two old friends against the backdrop of America’s cultural revolution. For small-town Iowa lawyer Sam McCain the year 1965 is not a sweet one. His father is gravely ill. His elitist boss is just now coming out of rehab. The brilliant lawyer he’d hoped to start a relationship with has gone back to her husband in Chicago. And first young soldier from Black River Falls returns home from a strange place called Viet Nam. In a coffin.

Against this background McCain tries to enjoy himself during the long Labor Day weekend party the town sponsors every year, reuniting with several old friends who appeared throughout the first six novels. Now that they’re all in their late twenties some of the old grudges and rivalries seem silly—until two of them are murdered for what seems to be a motive buried in the past.

With the Beatles, Rolling Stones, and Bob Dylan irritating those over thirty—and the boys in long hair and girls wearing blouses without bras irritating people even more—Sam McCain is forced to realize that his old world, along with the entire country’s, is about to end forever.

My two m-spikes

I wanted to post my results, and got a little behind! Here it is:

SERUM PROTEIN ELECTROPHORESIS: COMPARED TO 6/1/09, NO SIGNIFICANT CHANGE IN PREVIOUSLY CHARACTERIZED (2) IgA-LAMBDAS FROM 0.25 TO 0.26 G/dL AND FROM 0.19 TO 0.15 G/dL.

The two m-spikes have been staying this way for several months now. The complete bone survey report says, “No
aggressive lytic or sclerotic osseous lesions.”

Good, eh?

Dr. Brian Durie to host a teleconference

Dr. Brian Durie, Chairman and Medical Director of the International Myeloma Foundation, will host a teleconference next week to highlight key myeloma presentations at the upcoming American Society of Hematology Annual Meeting. The teleconference will take place on Monday, November 30th at 11 a.m. ET.

Discussion topics will include:
§ Treating the full cycle of myeloma
§ Pipeline drugs – what’s next and why they’re needed
§ Genetic variations in survival and outcome

Here are the dial-in details for the teleconference:

800.860.2442 (U.S.) or 412.858.4600 (outside of the U.S.)
Pass code: IMF

H1N1 flu that’s resistant to Tamiflu

I just read about a strain of H1N1 flu that’s resistant to Tamiflu. Four of these cases have been reported at Duke Medical Center in Durham, North Carolina.  I wondered if it has possibly infected people in the transplant clinic? A friend had her SCT at Duke one year when the flu was rampant in the transplant clinic.  She said that a few of the patients became quite ill.  She had the flu herself. She recovered and had a second stem cell transplant.

“All four of the North Carolina patients were hospitalized and were very ill with underlying severely compromised immune systems and multiple other complex medical conditions, according to researchers from the Duke University Medical Center. Three of the four died. No details have been released about how the patients caught the resistant virus or whether there was any contact among them.”

Maugh II, T.H. (2009, November 20). Swine flu seems to be trailing off — for now, at least. Retrieved from http://latimesblogs.latimes.com/booster_shots/2009/11/swine-flu-seems-to-be-tailing-offfor-now-at-elast.html

Three Harpsichords

We went to a concert Friday night in Chapel Hill that featured three harpsichords!  The program included music by Bach and a local composer named Edwin McLean.  I really enjoyed McLean’s music, and will be looking for a CD.

Harpsichord concert

One of the performers, Elaine Funaro, played her new harpsichord (Opus 333). The instrument was built by Richard Kingston. The harpsichord was painted by Durham artist Lisa Creed.

Richard Kingston